2023, Vol. 4, Issue 2, Part B
Polyoxometalate based nanohybrid: Study of its antimicrobial activity
Author(s): Shiva Arun, Roop Kumar, Susheel Kumar Singh, Amit Kumar Tripathi, Krishna Srivastava and Puspendra Singh
Abstract: The study of nanohybrids made by encasing polyoxometalates (POMs) in chitosan and their potential uses in medicine is a rapidly developing topic. This study involved the synthesis of a polyoxometalate (K8SiW11O39) possessing a lacunary position in its Keggin type structure. Followed by insertion of alkylsilane into the lacunary location. It was subsequently subjected to a reaction with 2-hydroxy-1-naphtaldehyde, Ferric metalation, and then encapsulation into chitosan via the ionotropic gelation process, wherein the POM and the chitosan functioned as an anion and cation, respectively. The bands present in the UV-Vis spectra at distinct wavelengths signify the successful insertion of the alkylsilane into K8SiW11O39, followed by Fe metalization. In order to create the final nanohybrid, its encapsulation into chitosan has been verified by UV-Vis spectroscopy. Moreover, FT-IR analysis was used to characterize chitosan, POM injected with alkylsilane, and nanohybrid. The complete set of anticipated elements is present in the nanohybrid, according to EDX analysis. Bacterial strains of B. subtilis gram (+)ve and E. Coli gram (-)ve were used to assess the antibacterial activity of POM implanted with alkylsilane and Nanohybrid. Comparing the nanohybrid to bare POM injected with metallated alkylsilane and chitosan has improved the hybrid's antibacterial activity.
Pages: 111-117 | Views: 230 | Downloads: 88
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How to cite this article:
Shiva Arun, Roop Kumar, Susheel Kumar Singh, Amit Kumar Tripathi, Krishna Srivastava, Puspendra Singh. Polyoxometalate based nanohybrid: Study of its antimicrobial activity. J Res Chem 2023;4(2):111-117.
