2024, Vol. 5, Issue 2, Part A
Phytochemical profiling and structural elucidation of active compounds in Momordica charantia L.
Author(s): Nourhan Abdel- Fathi
Abstract: Momordica charantia L. (bitter gourd) is a well-known medicinal plant consumed as both a vegetable and a therapeutic agent in many parts of the world. Its distinctive bitterness reflects a unique reservoir of bioactive compounds, ranging from cucurbitane-type triterpenoids and saponins to phenolics, flavonoids, and bioactive peptides. These compounds have been linked to diverse pharmacological activities, including antidiabetic, anticancer, antioxidant, and antimicrobial effects. Phytochemical profiling provides a systematic framework for identifying and quantifying these constituents, while structural elucidation offers insights into their molecular architecture, stereochemistry, and functional groups that determine biological activity. This paper reviews the methodologies for phytochemical profiling of M. charantia using modern chromatographic and spectroscopic techniques, summarizes the major classes of bioactive constituents, and highlights structural elucidation studies that have clarified the chemistry of compounds such as charantin, momordicosides, karavilagenins, and polypeptide-p. By integrating traditional knowledge with advanced phytochemical analysis, bitter gourd emerges as a plant of continuing importance in nutraceutical and pharmaceutical research.
Pages: 125-127 | Views: 405 | Downloads: 272
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How to cite this article:
Nourhan Abdel- Fathi. Phytochemical profiling and structural elucidation of active compounds in Momordica charantia L.. J Res Chem 2024;5(2):125-127.
