2025, Vol. 6, Issue 1, Part A
Antioxidant activity of Mesua ferrea
Author(s): Yasir Arafat Lone, Sudhanshu Dhar Dwivedi and Sheeraz Ahmad Wagay
Abstract: Mesua ferrea, commonly known as the Ceylon ironwood or Nagkesar, is a medicinal plant widely recognized for its therapeutic potential. This study focuses on evaluating the antioxidant properties of Mesua ferrea using various in vitro assays. The plant's flowers, seeds, and leaves were subjected to extraction using solvents such as methanol, ethanol, and aqueous solutions. The extracts were then analyzed for their free radical scavenging activity using assays like DPPH (2,2-diphenyl-1-picrylhydrazyl), ABTS (2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid), FRAP (ferric reducing antioxidant power), and nitric oxide scavenging. Phytochemical analysis revealed the presence of bioactive compounds such as flavonoids, tannins, phenolic acids, and terpenoids, which are known contributors to antioxidant activity. Among the tested extracts, the methanolic extract showed the highest free radical scavenging activity, with an IC50 value comparable to standard antioxidants like ascorbic acid and trolox. The study highlights the potential of Mesua ferrea as a natural antioxidant source, which could be utilized in pharmaceuticals, nutraceuticals, and food industries to combat oxidative stress-related disorders. Further in vivo studies and characterization of the active compounds are recommended to validate and explore its full therapeutic potential.
Pages: 04-06 | Views: 31 | Downloads: 19
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How to cite this article:
Yasir Arafat Lone, Sudhanshu Dhar Dwivedi, Sheeraz Ahmad Wagay. Antioxidant activity of Mesua ferrea. J Res Chem 2025;6(1):04-06.
