2025, Vol. 6, Issue 1, Part C
A novel synthesis, characterization and antibacterial studies of quinazolines derivative
Author(s): Nasrin Parween and Arun Kumar Yadav
Abstract: A novel synthesis, Characterization and their antibacterial studies of benzoderivative of quinazolines has been reported. 3-nitro anilines are reacted with chloroacetyl chloride in presence of acetone to give 2-chloro-N-(3-nitrophenyl)acetamide which when reacted with 2-amino-4-(4-chlorophenyl)-1,4-dihydrocinnolin-3(2H)-one in presence of dry pyridine to give the final target. The structures of synthesized compounds are confirmed by their IR and 1H-NMR spectral data. Melting point of the compound has been determined by open capillary tube and hence uncorrected. TLC of the compound has been carried out by using n-hex: EA (1:1) solvent.
DOI: 10.22271/reschem.2025.v6.i1c.194
Pages: 208-209 | Views: 334 | Downloads: 106
Download Full Article: Click Here
How to cite this article:
Nasrin Parween, Arun Kumar Yadav. A novel synthesis, characterization and antibacterial studies of quinazolines derivative. J Res Chem 2025;6(1):208-209. DOI: 10.22271/reschem.2025.v6.i1c.194
