2025, Vol. 6, Issue 2, Part A
Docking related survey on heterocyclic compounds based on Mur-F enzyme inhibitors and their antimicrobial potential
Author(s): Manisha, Dolly, Swati Rana, Gaurav Agarwal, Mamta Rani and Sonia Narwal
Abstract: Heterocyclic compounds represent one of the most significant and diverse classes of organic molecules. In recent years, interest in these compounds has grown substantially due to their broad range of applications in both synthetic chemistry and biomedical research. Notably, many heterocyclic structures exhibit potent antibacterial properties, showing effectiveness against a wide spectrum of Gram-positive and Gram-negative bacterial species. Their structural versatility and ability to interact with various biological targets make them valuable candidates in the development of new antimicrobial agents. Some of the derivatives of these compounds show excellent antimicrobial and antibacterial activity. Heterocyclic compounds have been reported anti-atherosclerotic, antidibetic, antiviral, antihypertensive, antibacterial, antihistaminic, anticancer, antispasmodic, anti-inflammatory, antiallergic, neurotropic and analgesic activities. The new antimicrobial compounds deactivate the enzyme serve as a novel approach for researchers. The molecular docking technique helps to find out the new drugs molecule by acting on new targets. This review highlights heterocyclic compounds that have been investigated for their antimicrobial properties by using Mur -F enzyme as target. The results of in-vitro and in-silico have been compared and critically discussed.
Pages: 30-36 | Views: 143 | Downloads: 51
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How to cite this article:
Manisha, Dolly, Swati Rana, Gaurav Agarwal, Mamta Rani, Sonia Narwal. Docking related survey on heterocyclic compounds based on Mur-F enzyme inhibitors and their antimicrobial potential. J Res Chem 2025;6(2):30-36.
